How is syphilis typically treated in its early stages?

Benzathine penicillin G is the recommended treatment for early-stage syphilis. This antibiotic is highly effective against Treponema pallidum, the bacterium that causes syphilis. In the early stages, prompt treatment with Benzathine penicillin G can lead to complete resolution of the infection and prevent further complications and progression to later stages of the disease.

This specific formulation of penicillin is given as a long-acting intramuscular injection. Its pharmacokinetics are suitable for effectively targeting the bacteria in the body and eliminating the infection. Benzathine penicillin G is the standard treatment because of its proven efficacy and safety profile, making it the first-line choice in clinical guidelines.

Other options, while they may be effective against different pathogens or infections, do not align with the established protocols for treating syphilis. Azithromycin, for example, is not recommended as a primary treatment due to concerns over resistance and inadequate efficacy. Tetracycline can also be effective but is not the first choice due to potential side effects and contraindications, especially in pregnant women and children. Metronidazole is primarily used for bacterial and parasitic infections and does not have activity against Treponema pallidum. Therefore,