What is a common sign of a primary immunodeficiency in children?

Frequent ear infections are a common sign of a primary immunodeficiency in children because these conditions result in an impaired immune response, making children more susceptible to infections, particularly in the respiratory and ear regions. The immune system plays a crucial role in defending against pathogens, and when it is functioning poorly due to a primary immunodeficiency, even common infections can persist or recur frequently.

Children with primary immunodeficiency may experience multiple episodes of otitis media (ear infections) that don't respond well to typical treatments, indicating a more systemic issue with their immune function. This highlights the importance of recognizing such signs, as early diagnosis can lead to effective management and treatment options to improve the child’s health and quality of life.

Other options, while they may indicate various health concerns, do not specifically point to the typical manifestations associated with primary immunodeficiencies in the same way that recurrent infections do.